AK2 Antibody (C-term) Blocking Peptide

Background:
Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis.

Other Names: Adenylate kinase 2, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03168}, AK 2 {ECO:0000255|HAMAP-Rule:MF_03168}, 2743 {ECO:0000255|HAMAP-Rule:MF_03168}, ATP-AMP transphosphorylase 2 {ECO:0000255|HAMAP-Rule:MF_03168}, ATP:AMP phosphotransferase {ECO:0000255|HAMAP-Rule:MF_03168}, Adenylate monophosphate kinase {ECO:0000255|HAMAP-Rule:MF_03168}, Adenylate kinase 2, mitochondrial, N-terminally processed {ECO:0000255|HAMAP-Rule:MF_03168}, AK2 {ECO:0000255|HAMAP-Rule:MF_03168}, ADK2

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8134b was selected from the C-term region of human AK2 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Type: Synthetic peptide

Primary Accession: P54819

Gene ID: 204

Gene Name: AK2 {ECO:0000255|HAMAP-Rule:MF_03168}

Format: The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.

Bio References:
Noma, T., et al., Biochim. Biophys. Acta 1395(1):34-39 (1998).Lee, Y., et al., J. Biochem. 123(1):47-54 (1998).Lee, Y., et al., Biochem. Mol. Biol. Int. 39(4):833-842 (1996).Bruns, G.A., et al., Biochem. Genet. 15 (5-6), 477-486 (1977).