AK3 Antibody (C-term T208) Blocking Peptide

Background:
AK3 is a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. A pseudogene for the AK3 gene has been located on chromosome 17. Three transcript variants encoding the same protein have been identified for this gene, which sequence alignment suggests is located on chromosome 1.

Other Names: Adenylate kinase 4, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03170}, AK 4 {ECO:0000255|HAMAP-Rule:MF_03170}, 27410 {ECO:0000255|HAMAP-Rule:MF_03170}, 2746 {ECO:0000255|HAMAP-Rule:MF_03170}, Adenylate kinase 3-like {ECO:0000255|HAMAP-Rule:MF_03170}, GTP:AMP phosphotransferase AK4 {ECO:0000255|HAMAP-Rule:MF_03170}, AK4 {ECO:0000255|HAMAP-Rule:MF_03170}

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8132d was selected from the C-term region of human AK3 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Type: Synthetic peptide

Primary Accession: P27144

Gene ID: 205

Gene Name: AK4 {ECO:0000255|HAMAP-Rule:MF_03170}

Format: The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.

Bio References:
Biochem. J. 358 (PT 1), 225-232 (2001)Eur. J. Biochem. 261(2):509-517 (1999). Brain Res. Mol. Brain Res. 62(2):187-195 (1998). Genomics 13(3):537-542 (1992). Cytogenet. Cell Genet. 32 (1-4), 144-152 (1982).