AKR1B1 Antibody (C-term) Blocking Peptide

AKR1B1 Antibody (C-term) Blocking Peptide

€293.00
In stock
SKU
AC-BP2735b
Catalog Number: AC-BP2735b
Size: 500 µg
Datasheet

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Background:
AKR1B1 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This protein catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol.

Other Names: Aldose reductase, AR, Aldehyde reductase, Aldo-keto reductase family 1 member B1, AKR1B1, ALDR1

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2735b was selected from the C-term region of human AKR1B1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Type: Synthetic peptide

Primary Accession: P15121

Gene ID: 231

Gene Name: AKR1B1

Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.

Bio References:
Steuber,H.,J. Mol. Biol. 379 (5), 991-1016 (2008)Gleissner,C.A.,Arterioscler. Thromb. Vasc. Biol. 28 (6), 1137-1143 (2008)Grundmann,U.,DNA Cell Biol. 9 (3), 149-157 (1990)
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