AKR1C1 Antibody (Center) Blocking peptide

AKR1C1 Antibody (Center) Blocking peptide

€293.00
In stock
SKU
AC-BP5331c
Catalog Number: AC-BP5331c
Size: 500 µg
Datasheet

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Background:
AKR1C1 encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This protein shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Other Names: Aldo-keto reductase family 1 member C1, 111-, 20-alpha-hydroxysteroid dehydrogenase, 20-alpha-HSD, Chlordecone reductase homolog HAKRC, Dihydrodiol dehydrogenase 1/2, DD1/DD2, High-affinity hepatic bile acid-binding protein, HBAB, Indanol dehydrogenase, Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase, AKR1C1, DDH, DDH1

Type: Synthetic peptide

Primary Accession: Q04828

Other Accession: NP_001344.2

Gene ID: 1645

Gene Name: AKR1C1

Format: The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.

Bio References:
Reding, K.W., et al. Am. J. Epidemiol. 170(10):1241-1249(2009)Chien, C.W., et al. Carcinogenesis 30(10):1813-1820(2009)Davies, N.J., et al. Cancer Res. 69(11):4769-4775(2009)
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