AKR1C4 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS8891
Background:
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Alternative Name:
Aldo-keto reductase family 1 member C4, 3-alpha-HSD1, 3-alpha-hydroxysteroid dehydrogenase type I, Chlordecone reductase, CDR, Dihydrodiol dehydrogenase 4, DD-4, DD4, HAKRA, AKR1C4, CHDR
Application Dilution: WB: 1:500~1:2000
Specificity: AKR1C4 polyclonal antibody detects endogenous levels of AKR1C4 protein.
Immunogen:
Recombinant full length Human AKR1C4.
MW: ~ 37kDa
Swis Prot.: P17516
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Alternative Name:
Aldo-keto reductase family 1 member C4, 3-alpha-HSD1, 3-alpha-hydroxysteroid dehydrogenase type I, Chlordecone reductase, CDR, Dihydrodiol dehydrogenase 4, DD-4, DD4, HAKRA, AKR1C4, CHDR
Application Dilution: WB: 1:500~1:2000
Specificity: AKR1C4 polyclonal antibody detects endogenous levels of AKR1C4 protein.
Immunogen:
Recombinant full length Human AKR1C4.
MW: ~ 37kDa
Swis Prot.: P17516
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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