AKT1 Antibody (C-term T450) Blocking peptide

AKT1 Antibody (C-term T450) Blocking peptide

€363.00
In stock
SKU
AC-BP11976a
Catalog Number: AC-BP11976a
Size: 500 µg
Datasheet
Request Information
Background:
The serine-threonine protein kinase encoded by the AKT1gene is catalytically inactive in serum-starved primary andimmortalized fibroblasts. AKT1 and the related AKT2 are activatedby platelet-derived growth factor. The activation is rapid andspecific, and it is abrogated by mutations in the pleckstrinhomology domain of AKT1. It was shown that the activation occursthrough phosphatidylinositol 3-kinase. In the developing nervoussystem AKT is a critical mediator of growth factor-induced neuronalsurvival. Survival factors can suppress apoptosis in atranscription-independent manner by activating the serine/threoninekinase AKT1, which then phosphorylates and inactivates componentsof the apoptotic machinery. Multiple alternatively splicedtranscript variants have been found for this gene. [provided byRefSeq].

Other Names:
RAC-alpha serine/threonine-protein kinase, Protein kinase B, PKB, Protein kinase B alpha, PKB alpha, Proto-oncogene c-Akt, RAC-PK-alpha, AKT1, PKB, RAC

Gene Name: AKT1

Gene ID: 207
Primary Accession: P31749
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
More Information
Is Featured? No
Write Your Own Review
You're reviewing:AKT1 Antibody (C-term T450) Blocking peptide