AKT1 (clone IML-26), anti-human, mouse, rat, chicken
€347.00
In stock
SKU
251792
Catalog Nr.: 251792
Size: 0.1 mg
Isotype: Mouse IgG1
Applications: E, WB
Size: 0.1 mg
Isotype: Mouse IgG1
Applications: E, WB
Protein Family: Enzymes, Protein Kinases
Pathway and Disease: Signal Transduction, Cell Growth and Death, Cell Communication, Immune System, Endocrine System, Nervous and Sensory Systems, Development and Behavior, Cancers, Infectious Diseases
Description:
Proto-oncogene c-Akt (AKT1) plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation. Defects in AKT1 are a cause of susceptibility to breast cancer (BC), a common malignancy originating from breast epithelial tissue. Breast neoplasms can be distinguished by their histologic pattern. Invasive ductal carcinoma is by far the most common type.
Alternate Names: RAC-alpha serine/threonine-protein kinase, RAC-PK-alpha, Protein kinase B, PKB, C-AKT, AKT1, RAC
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: P31749
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human AKT1.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Signal Transduction, Cell Growth and Death, Cell Communication, Immune System, Endocrine System, Nervous and Sensory Systems, Development and Behavior, Cancers, Infectious Diseases
Description:
Proto-oncogene c-Akt (AKT1) plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation. Defects in AKT1 are a cause of susceptibility to breast cancer (BC), a common malignancy originating from breast epithelial tissue. Breast neoplasms can be distinguished by their histologic pattern. Invasive ductal carcinoma is by far the most common type.
Alternate Names: RAC-alpha serine/threonine-protein kinase, RAC-PK-alpha, Protein kinase B, PKB, C-AKT, AKT1, RAC
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: P31749
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human AKT1.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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