AKT2 Antibody (S474) Blocking Peptide
€293.00
In stock
SKU
AC-BP7029d
Background:
AKT2 is a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. AKT2 has been shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression of AKT2 contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. AKT2 is a general protein kinase capable of phophorylating several known proteins.
Other Names: RAC-beta serine/threonine-protein kinase, Protein kinase Akt-2, Protein kinase B beta, PKB beta, RAC-PK-beta, AKT2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7029d was selected from the S474 region of human AKT2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: P31751
Gene ID: 208
Gene Name: AKT2
Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Bio References:
George, S., et al., Science 304(5675):1325-1328 (2004).Xu, X., et al., Oncol. Rep. 11(1):25-32 (2004).Shim, D., et al., Arch. Biochem. Biophys. 425(2):214-220 (2004).Li, X., et al., Gastroenterology 126(1):122-135 (2004).Vojtek, A.B., et al., Mol. Cell. Biol. 23(13):4417-4427 (2003).
AKT2 is a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. AKT2 has been shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression of AKT2 contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. AKT2 is a general protein kinase capable of phophorylating several known proteins.
Other Names: RAC-beta serine/threonine-protein kinase, Protein kinase Akt-2, Protein kinase B beta, PKB beta, RAC-PK-beta, AKT2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7029d was selected from the S474 region of human AKT2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: P31751
Gene ID: 208
Gene Name: AKT2
Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Bio References:
George, S., et al., Science 304(5675):1325-1328 (2004).Xu, X., et al., Oncol. Rep. 11(1):25-32 (2004).Shim, D., et al., Arch. Biochem. Biophys. 425(2):214-220 (2004).Li, X., et al., Gastroenterology 126(1):122-135 (2004).Vojtek, A.B., et al., Mol. Cell. Biol. 23(13):4417-4427 (2003).
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