AKT2 (clone 1B6), anti-human, rat, monkey
€394.00
In stock
SKU
252962
Catalog Nr.: 252962
Size: 0.1 ml
Isotype: Mouse IgG2b
Applications: E, WB, IF, IHC
Size: 0.1 ml
Isotype: Mouse IgG2b
Applications: E, WB, IF, IHC
Protein Family: Enzymes, Protein Kinases
Pathway and Disease: Cancers, Cell Communication, Cell Growth and Death, Endocrine System, Immune System, Signal Transduction
Description:
AKT2 (RAC-beta serine/threonine-protein kinase) belongs to the AKT serine/threonine-protein kinase family with AKT1 and AKT3. AKT2 signals downstream of phosphatidylinositol 3-kinase (PI3K) to mediate the effects of various growth factors such as PDGF, EGF and IGF-I. Two specific sites, one in the kinase domain (Thr-309) and the other in the C-terminal regulatory region (Ser-474) need to be phosphorylated for AKT2 full activation.
Alternate Names: RAC-beta serine/threonine-protein kinase, RAC-PK-beta, Protein kinase Akt-2, Protein kinase B beta, PKB beta, AKT2
Application Notes: E: 1:10000; WB: 1:500-1:2000; IF: 1:200-1:1000; IHC: 1:200-1:1000
Accession No.: P31751
Antigen: Purified recombinant fragment of human Akt2 expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Cancers, Cell Communication, Cell Growth and Death, Endocrine System, Immune System, Signal Transduction
Description:
AKT2 (RAC-beta serine/threonine-protein kinase) belongs to the AKT serine/threonine-protein kinase family with AKT1 and AKT3. AKT2 signals downstream of phosphatidylinositol 3-kinase (PI3K) to mediate the effects of various growth factors such as PDGF, EGF and IGF-I. Two specific sites, one in the kinase domain (Thr-309) and the other in the C-terminal regulatory region (Ser-474) need to be phosphorylated for AKT2 full activation.
Alternate Names: RAC-beta serine/threonine-protein kinase, RAC-PK-beta, Protein kinase Akt-2, Protein kinase B beta, PKB beta, AKT2
Application Notes: E: 1:10000; WB: 1:500-1:2000; IF: 1:200-1:1000; IHC: 1:200-1:1000
Accession No.: P31751
Antigen: Purified recombinant fragment of human Akt2 expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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