AKT2 polyclonal, anti-human

Protein Family: Enzymes, Protein Kinases

Pathway and Disease: Cancers, Cell Communication, Cell Growth and Death, Endocrine System, Immune System, Signal Transduction

Description:
AKT2 (RAC-beta serine/threonine-protein kinase) belongs to the AKT serine/threonine-protein kinase family with AKT1 and AKT3. AKT2 signals downstream of phosphatidylinositol 3-kinase (PI3K) to mediate the effects of various growth factors such as PDGF, EGF, and IGF-I. Two specific sites, one in the kinase domain (Thr-309) and the other in the C-terminal regulatory region (Ser-474) need to be phosphorylated for AKT2 full activation.

Alternate Names: RAC-beta serine/threonine-protein kinase, RAC-PK-beta, Protein kinase Akt-2, Protein kinase B beta, PKB beta, AKT2

Application Notes: E: 1:1,000-1:10,000; WB: 1:200-1:1,000; IHC: 1:50-1:200

Accession No.: P31751

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human AKT2.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.