AKTIP Antibody(C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP19369b
Background:
The mouse homolog of this gene produces fused toes andthymic hyperplasia in heterozygous mutant animals while homozygousmutants die in early development. This gene may play a role inapoptosis as these morphological abnormalities are caused byaltered patterns of programmed cell death. The protein encoded bythis gene is similar to the ubiquitin ligase domain of otherubiquitin-conjugating enzymes but lacks the conserved cysteineresidue that enables those enzymes to conjugate ubiquitin to thetarget protein. This protein interacts directly withserine/threonine kinase protein kinase B (PKB)/Akt and modulatesPKB activity by enhancing the phosphorylation of PKB's regulatorysites. Alternative splicing results in two transcript variantsencoding the same protein.
Other Names:
AKT-interacting protein, Ft1, Fused toes protein homolog, AKTIP, FTS
Gene Name: AKTIP (HGNC:16710)
Gene ID: 64400
Primary Accession: Q9H8T0
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The mouse homolog of this gene produces fused toes andthymic hyperplasia in heterozygous mutant animals while homozygousmutants die in early development. This gene may play a role inapoptosis as these morphological abnormalities are caused byaltered patterns of programmed cell death. The protein encoded bythis gene is similar to the ubiquitin ligase domain of otherubiquitin-conjugating enzymes but lacks the conserved cysteineresidue that enables those enzymes to conjugate ubiquitin to thetarget protein. This protein interacts directly withserine/threonine kinase protein kinase B (PKB)/Akt and modulatesPKB activity by enhancing the phosphorylation of PKB's regulatorysites. Alternative splicing results in two transcript variantsencoding the same protein.
Other Names:
AKT-interacting protein, Ft1, Fused toes protein homolog, AKTIP, FTS
Gene Name: AKTIP (HGNC:16710)
Gene ID: 64400
Primary Accession: Q9H8T0
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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