ALAD Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP6828b
Background:
The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria.
Other Names:
Delta-aminolevulinic acid dehydratase, ALADH, Porphobilinogen synthase, ALAD
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6828b was selected from the C-term region of human ALAD. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: ALAD
Gene ID: 210
Primary Accession: P13716
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria.
Other Names:
Delta-aminolevulinic acid dehydratase, ALADH, Porphobilinogen synthase, ALAD
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6828b was selected from the C-term region of human ALAD. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: ALAD
Gene ID: 210
Primary Accession: P13716
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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