ALDH1A1 (Aldehyde Dehydrogenase 1A1) [clone ALDH1A1/1381], anti-human

Description: ALDH1A1 belongs to the ALDH enzymes, a family of evolutionarily conserved enzymes comprised of 19 isoforms that are localized in the cytoplasm, mitochondria or nucleus. ALDH1A1 is predominantly expressed in the epithelium of testis, brain, eye, liver, kidney, as well as neural and hematopoietic stem cells. Reportedly, high ALDH1A1 expression is found in solitary fibrous tumor (SFT) and hemangiopericytoma (HPC), compared to meningiomas and synovial sarcomas. In combination with CD34, ALDH1A1 may be useful for the differentiation among SFT, HPC, meningioma, and synovial sarcoma.Localization: cytoplasmDilution: 50-200Positive Control: Colon or Testicular Carcinoma, HepG2 or A549 cellsHIER: citrate pH6.0Status: RUO