ALDOB Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP18830a
Background:
Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is atetrameric glycolytic enzyme that catalyzes the reversibleconversion of fructose-1,6-bisphosphate to glyceraldehyde3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3aldolase isozymes which are distinguished by their electrophoreticand catalytic properties. Differences indicate that aldolases A, B,and C are distinct proteins, the products of a family of related'housekeeping' genes exhibiting developmentally regulatedexpression of the different isozymes. The developing embryoproduces aldolase A, which is produced in even greater amounts inadult muscle where it can be as much as 5% of total cellularprotein. In adult liver, kidney and intestine, aldolase Aexpression is repressed and aldolase B is produced. In brain andother nervous tissue, aldolase A and C are expressed about equally.There is a high degree of homology between aldolase A and C.Defects in ALDOB cause hereditary fructose intolerance. [providedby RefSeq].
Other Names:
Fructose-bisphosphate aldolase B, Liver-type aldolase, ALDOB, ALDB
Gene Name: ALDOB {ECO:0000303|PubMed:15880727, ECO:0000312|HGNC:HGNC:417}
Gene ID: 229
Primary Accession: P05062
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is atetrameric glycolytic enzyme that catalyzes the reversibleconversion of fructose-1,6-bisphosphate to glyceraldehyde3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3aldolase isozymes which are distinguished by their electrophoreticand catalytic properties. Differences indicate that aldolases A, B,and C are distinct proteins, the products of a family of related'housekeeping' genes exhibiting developmentally regulatedexpression of the different isozymes. The developing embryoproduces aldolase A, which is produced in even greater amounts inadult muscle where it can be as much as 5% of total cellularprotein. In adult liver, kidney and intestine, aldolase Aexpression is repressed and aldolase B is produced. In brain andother nervous tissue, aldolase A and C are expressed about equally.There is a high degree of homology between aldolase A and C.Defects in ALDOB cause hereditary fructose intolerance. [providedby RefSeq].
Other Names:
Fructose-bisphosphate aldolase B, Liver-type aldolase, ALDOB, ALDB
Gene Name: ALDOB {ECO:0000303|PubMed:15880727, ECO:0000312|HGNC:HGNC:417}
Gene ID: 229
Primary Accession: P05062
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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