ALOXE3 Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP10450c
Background:
ALOXE3 is a member of the lipoxygenase family, whichare catabolized by arachidonic acid-derived compounds. The encodedenzyme is a hydroperoxide isomerase that synthesizes a unique typeof epoxy alcohol (8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoicacid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). Thisepoxy alcohol can activate the the nuclear receptor peroxisomeproliferator-activated receptor alpha (PPARalpha), which isimplicated in epidermal differentiation. Loss of function of theenzyme encoded by this gene results in ichthyosis, implicating thefunction of this gene in the differentiation of human skin.
Other Names:
Hydroperoxide isomerase ALOXE3, Epidermis-type lipoxygenase 3, Epidermal LOX-3, e-LOX-3, eLOX-3, Hydroperoxy icosatetraenoate dehydratase, ALOXE3
Gene Name: ALOXE3 (HGNC:13743)
Gene ID: 59344
Primary Accession: Q9BYJ1
Other Accession: NP_067641.2;NP_001159432.1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
ALOXE3 is a member of the lipoxygenase family, whichare catabolized by arachidonic acid-derived compounds. The encodedenzyme is a hydroperoxide isomerase that synthesizes a unique typeof epoxy alcohol (8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoicacid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). Thisepoxy alcohol can activate the the nuclear receptor peroxisomeproliferator-activated receptor alpha (PPARalpha), which isimplicated in epidermal differentiation. Loss of function of theenzyme encoded by this gene results in ichthyosis, implicating thefunction of this gene in the differentiation of human skin.
Other Names:
Hydroperoxide isomerase ALOXE3, Epidermis-type lipoxygenase 3, Epidermal LOX-3, e-LOX-3, eLOX-3, Hydroperoxy icosatetraenoate dehydratase, ALOXE3
Gene Name: ALOXE3 (HGNC:13743)
Gene ID: 59344
Primary Accession: Q9BYJ1
Other Accession: NP_067641.2;NP_001159432.1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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