Alpha-CGRP (clone ), anti-human, rat
€922.00
In stock
SKU
250238
Catalog Nr.: 250238
Size: 0.2 mg
Isotype: Mouse IgG1
Applications: E, IHC
Size: 0.2 mg
Isotype: Mouse IgG1
Applications: E, IHC
Protein Family: Hormones, Receptors and Channels
Pathway and Disease: Endocrine System, Nervous and Sensory Systems
Description:
Calcitonin gene-related peptide is a 37 amino-acid vasoactive neuropeptide (MW 3789) widely expressed throughout the central and peripheral nervous system. CGRP has potent vasodilatory effects probably serving as a regulator of regional blood flow, in addition to a variety of other cellular effects. This antibody binds an epitope within the aa 1-18 of human alpha-CGRP. Based on inhibition ELISA, this antibody shows full cross-reactivity with rat alpha-CGRP and about 50% cross-reactivity with human beta-CGRP. Cross-reactivity with coated rat alpha-CGRP is low (8%) and there is no cross-reaction with human amylin.
Alternate Names: Calcitonin gene-related peptide 1 (Precursor), CGRP-1, Alpha-type CGRP
Application Notes: Product Cat. No. 250238 binds free alpha-CGRP in solution. Based on inhibition ELISA, the affinity of Product Cat. No. 250238 is at least 24 fold higher than the one of Product Cat. No. 250237. The ELISA dilution guideline applies to human alpha-CGRP coated directly at 1.0 ug/mL. Product Cat. No. 250238 (as capture antibody) forms a sandwich ELISA pair with Product Cat. No. 250237 (as biotinylated detection antibody) for measuring human alpha-CGRP, giving a detection limit of 0.13 nmol/L in an unoptimized buffer assay. The antibody is used in IHC with paraffin-embedded tissues. E: 1:2,000; IHC: 1:200-1:400
Accession No.: P06881
Antigen: Synthetic human alpha-CGRP adsorbed onto aluminum hydroxide gel
Format: Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Endocrine System, Nervous and Sensory Systems
Description:
Calcitonin gene-related peptide is a 37 amino-acid vasoactive neuropeptide (MW 3789) widely expressed throughout the central and peripheral nervous system. CGRP has potent vasodilatory effects probably serving as a regulator of regional blood flow, in addition to a variety of other cellular effects. This antibody binds an epitope within the aa 1-18 of human alpha-CGRP. Based on inhibition ELISA, this antibody shows full cross-reactivity with rat alpha-CGRP and about 50% cross-reactivity with human beta-CGRP. Cross-reactivity with coated rat alpha-CGRP is low (8%) and there is no cross-reaction with human amylin.
Alternate Names: Calcitonin gene-related peptide 1 (Precursor), CGRP-1, Alpha-type CGRP
Application Notes: Product Cat. No. 250238 binds free alpha-CGRP in solution. Based on inhibition ELISA, the affinity of Product Cat. No. 250238 is at least 24 fold higher than the one of Product Cat. No. 250237. The ELISA dilution guideline applies to human alpha-CGRP coated directly at 1.0 ug/mL. Product Cat. No. 250238 (as capture antibody) forms a sandwich ELISA pair with Product Cat. No. 250237 (as biotinylated detection antibody) for measuring human alpha-CGRP, giving a detection limit of 0.13 nmol/L in an unoptimized buffer assay. The antibody is used in IHC with paraffin-embedded tissues. E: 1:2,000; IHC: 1:200-1:400
Accession No.: P06881
Antigen: Synthetic human alpha-CGRP adsorbed onto aluminum hydroxide gel
Format: Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
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