Alpha Fetoprotein, AFP Human Native Protein (Active)

Description:
Purified human AFP protein

Background:
Alpha-fetoprotein(AFP) is a major plasma protein in the fetus, where it is produced by the yolk sac and liver,It is encoded by the AFPHYPERLINK "http://en.wikipedia.org/wiki/Gene" \o "Gene"gene.The AFP gene is located onHYPERLINK "http://en.wikipedia.org/wiki/Chromosome_4" \o "Chromosome 4"chromosome4q25.AFP is aHYPERLINK "http://en.wikipedia.org/wiki/Glycoprotein" \o "Glycoprotein"glycoproteinof 591 amino acids and a carbohydrate moiety.In rodent fetuses AFP bindsHYPERLINK "http://en.wikipedia.org/wiki/Estradiol" \o "Estradiol"estradiolto prevent the transport of this hormone across theHYPERLINK "http://en.wikipedia.org/wiki/Placenta" \o "Placenta"placenta. The main function of this is to prevent theHYPERLINK "http://en.wikipedia.org/wiki/Virilization" \o "Virilization"masculinizationof female fetuses.

Synonyms:
Alpha fetoprotein, alpha fetoglobulin, AFP, HPAFP

Application: ELISA

Formulation: Liquid

Storage buffer: Each vial contains 0.01 M PBS, 0.15 M NaCl (pH 7.4) with 0.05% NaN3.

Storage and Expiration:
Ship at 4℃.Upon receipt, aliquot and store at -20℃ or -80℃ for long term. Avoid repeated freeze and thaw cycles.