Alpha-Synuclein (C-term) polyclonal, anti-human, mouse, rat

Protein Family: Transporters

Pathway and Disease: Nervous and Sensory Systems, Neurodegenerative Disorders, Signaling Molecules and Interaction

Description:
The synucleins alpha, beta and gamma are presynaptic proteins abundant in neurons. Alpha-synuclein, a component of Alzheimer's disease amyloid plaques, is localized to neuronal cell bodies and synapses. Defects in alpha-synuclein are the cause of Parkinson disease type 1 and 4, Lewy body dementia, Alzheimer's disease, and Hallervorden-Spatz syndrome.

Alternate Names: Alpha-synuclein, non-A beta component of AD amyloid, non-A4 component of amyloid precursor, NACP, SNCA, NACP, PARK1

Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500

Accession No.: P37840

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human alpha-synuclein.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.