Alpha1-Antitrypsin (clone 3B7), anti-human
€407.00
In stock
SKU
250380
Catalog Nr.: 250380
Size: 0.1 mg
Isotype: Mouse IgG1
Applications: E, WB
Size: 0.1 mg
Isotype: Mouse IgG1
Applications: E, WB
Protein Family: Peptidases
Pathway and Disease: Metabolic Disorders, Immune System
Description:
The serum glycoprotein a1-antitrypsin also called a1- AT, is a typical member of the serpin family (serine protease inhibitors), and, an inhibitor of trypsin. a1- AT is synthesized in the liver thus as a single polypeptide chain of approximately 51 kDa showing a marked degree of genetic polymorphism due to the presence of over 20 different alleles. Individuals homozygous for a1- AT deficiency are predisposed to pulmonary emphysema and hepatic cirrhosis. This antibody is specific for human a1- AT (native and denatured).
Alternate Names: Alpha-1 protease inhibitor, Alpha-1-antiproteinase, a1-AT, alpha-1-antitrypsin, SERPINA1, serpin A1, SPAAT, AAT
Application Notes: Product Cat. No. 250380 reacts strongly in ELISA with native and denatured alpha1-AT coated directly onto the microtiter well. The antibody detects only native alpha1-AT in sandwich ELISA with a polyclonal capture antibody. Product Cat. No. 250380 reacts in western blot with native and denatured alpha1-AT in reduced as well as non-reduced forms. E: 1:15,000; WB: 1:1,000
Accession No.: P01009
Antigen: a1- AT isolated from human plasma
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Metabolic Disorders, Immune System
Description:
The serum glycoprotein a1-antitrypsin also called a1- AT, is a typical member of the serpin family (serine protease inhibitors), and, an inhibitor of trypsin. a1- AT is synthesized in the liver thus as a single polypeptide chain of approximately 51 kDa showing a marked degree of genetic polymorphism due to the presence of over 20 different alleles. Individuals homozygous for a1- AT deficiency are predisposed to pulmonary emphysema and hepatic cirrhosis. This antibody is specific for human a1- AT (native and denatured).
Alternate Names: Alpha-1 protease inhibitor, Alpha-1-antiproteinase, a1-AT, alpha-1-antitrypsin, SERPINA1, serpin A1, SPAAT, AAT
Application Notes: Product Cat. No. 250380 reacts strongly in ELISA with native and denatured alpha1-AT coated directly onto the microtiter well. The antibody detects only native alpha1-AT in sandwich ELISA with a polyclonal capture antibody. Product Cat. No. 250380 reacts in western blot with native and denatured alpha1-AT in reduced as well as non-reduced forms. E: 1:15,000; WB: 1:1,000
Accession No.: P01009
Antigen: a1- AT isolated from human plasma
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
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