Alpha1-Antitrypsin (clone 4E5), anti-human
€747.00
In stock
SKU
250376
Catalog Nr.: 250376
Size: 0.2 mg
Isotype: Mouse IgG1/k
Applications: E, WB
Size: 0.2 mg
Isotype: Mouse IgG1/k
Applications: E, WB
Protein Family: Peptidases
Pathway and Disease: Metabolic Disorders, Immune System
Description:
The serum glycoprotein a1-antitrypsin also called a1- AT, is a typical member of the serpin family (serine protease inhibitors), and, an inhibitor of trypsin. a1- AT is synthesized in the liver thus as a single polypeptide chain of approximately 51 kDa showing a marked degree of genetic polymorphism due to the presence of over 20 different alleles. Individuals homozygous for a1- AT deficiency are predisposed to pulmonary emphysema and hepatic cirrhosis. This antibody is specific for native human a-1 AT.
Alternate Names: Alpha-1 protease inhibitor, Alpha-1-antiproteinase
Application Notes: Product Cat. No. 250376 reacts strongly in ELISA with native alpha-1 AT directly coated onto the microtiter well. Product Cat. No. 250376 reacts in western blot with native alpha-1 AT in reduced as well as non-reduced form. E: 1:8,000; WB: 1:8,000
Accession No.: P01009
Antigen: a-1 AT isolated from human plasma
Format: Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Product Citations:
Chi-Yen S et al. 2013. IMSNA. 712-715.
Pathway and Disease: Metabolic Disorders, Immune System
Description:
The serum glycoprotein a1-antitrypsin also called a1- AT, is a typical member of the serpin family (serine protease inhibitors), and, an inhibitor of trypsin. a1- AT is synthesized in the liver thus as a single polypeptide chain of approximately 51 kDa showing a marked degree of genetic polymorphism due to the presence of over 20 different alleles. Individuals homozygous for a1- AT deficiency are predisposed to pulmonary emphysema and hepatic cirrhosis. This antibody is specific for native human a-1 AT.
Alternate Names: Alpha-1 protease inhibitor, Alpha-1-antiproteinase
Application Notes: Product Cat. No. 250376 reacts strongly in ELISA with native alpha-1 AT directly coated onto the microtiter well. Product Cat. No. 250376 reacts in western blot with native alpha-1 AT in reduced as well as non-reduced form. E: 1:8,000; WB: 1:8,000
Accession No.: P01009
Antigen: a-1 AT isolated from human plasma
Format: Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Product Citations:
Chi-Yen S et al. 2013. IMSNA. 712-715.
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