AMIGO-2 polyclonal, anti-human

Protein Family: Cell Adhesion Molecules

Pathway and Disease: Cancers, Cell Growth and Death, Cell Communication

Description:
Amphoterin-induced protein 2 (AMIGO-2) is required for depolarization-dependent survival of cultured cerebellar granule neurons. AMIGO-2 mediates homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. AMIGO-2 contributes to signal transduction through its intracellular domain, and is be required for tumorigenesis of a subset of gastric adenocarcinomas. AMIGO-2 is differentially expressed in 56% of thyroid, 57% of pancreatic and 45% of stomach cancers.

Alternate Names: Amphoterin-induced protein 2, AMIGO-2, Alivin-1, Differentially expressed in gastric adenocarcinomas, DEGA, AMIGO2, ALI1

Application Notes: E: 1:10,000-1:50,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: Q86SJ2

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human AMIGO-2.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.