Amoxicillin::BSA Conjugate
€0.00
In stock
SKU
BW-40110053
Product Description
Amoxicillin is a bactericidal penicillin active against both Gram-positive and Gram-negative organisms and is sensitive to β-Lactamase. It is bactericidal against sensitive organisms during the stage of active multiplication. Amoxicillin exerts its mode of action by interfering with bacterial cell wall synthesis by acylating the enzyme transpeptidase, thus rendering it unable to cross-link muramic acid containing peptidoglycan strands. This inhibition of the biosynthesis of peptidoglycan, a substance necessary for cell wall strength and rigidity, results in a defective cell wall.
BSA (bovine serum albumin) is conjugated to amoxicillin (1:182). The carboxyl group in amoxicillin is directly linked to an amine group in BSA, and/or carboxyl group in BSA is directly linked to the amine group in amoxicillin. Amoxicillin has a molecular weight of 365.4 Da and BSA has a molecular weight of 66.4 kDa. The resultant conjugation solution is then buffer-exchanged with 20 mM PBS, pH 7.4.
Conjugated BSA-amoxicillin is used to recognize amoxicillin-specific antibodies by ELISA and lateral flow based immunoassay. Product can be stored below -20°C for up to 1 year.
Hazmat Shipping: Non-hazardous
Storage: -20°C
Brand Name: bioPLUS
Amoxicillin is a bactericidal penicillin active against both Gram-positive and Gram-negative organisms and is sensitive to β-Lactamase. It is bactericidal against sensitive organisms during the stage of active multiplication. Amoxicillin exerts its mode of action by interfering with bacterial cell wall synthesis by acylating the enzyme transpeptidase, thus rendering it unable to cross-link muramic acid containing peptidoglycan strands. This inhibition of the biosynthesis of peptidoglycan, a substance necessary for cell wall strength and rigidity, results in a defective cell wall.
BSA (bovine serum albumin) is conjugated to amoxicillin (1:182). The carboxyl group in amoxicillin is directly linked to an amine group in BSA, and/or carboxyl group in BSA is directly linked to the amine group in amoxicillin. Amoxicillin has a molecular weight of 365.4 Da and BSA has a molecular weight of 66.4 kDa. The resultant conjugation solution is then buffer-exchanged with 20 mM PBS, pH 7.4.
Conjugated BSA-amoxicillin is used to recognize amoxicillin-specific antibodies by ELISA and lateral flow based immunoassay. Product can be stored below -20°C for up to 1 year.
Hazmat Shipping: Non-hazardous
Storage: -20°C
Brand Name: bioPLUS
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