AMPK alpha (PRKAA1) Antibody (S487) Blocking peptide
€293.00
In stock
SKU
AC-BP7260a
Background:
PRKAA1 belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways.
Other Names: 5'-AMP-activated protein kinase catalytic subunit alpha-1, AMPK subunit alpha-1, Acetyl-CoA carboxylase kinase, ACACA kinase, Hydroxymethylglutaryl-CoA reductase kinase, HMGCR kinase, Tau-protein kinase PRKAA1, PRKAA1, AMPK1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7260a was selected from the S487 region of human PRKAA1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: Q13131
Other Accession: Q86VS1
Gene ID: 5562
Gene Name: PRKAA1
Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Bio References:
Pang,T., J. Biol. Chem. 282 (1), 495-506 (2007)Crawford,R.M., Cell. Signal. 18 (10), 1595-1603 (2006)Crawford,R.M., Mol. Cell. Biol. 26 (15), 5921-5931 (2006)
PRKAA1 belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways.
Other Names: 5'-AMP-activated protein kinase catalytic subunit alpha-1, AMPK subunit alpha-1, Acetyl-CoA carboxylase kinase, ACACA kinase, Hydroxymethylglutaryl-CoA reductase kinase, HMGCR kinase, Tau-protein kinase PRKAA1, PRKAA1, AMPK1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7260a was selected from the S487 region of human PRKAA1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: Q13131
Other Accession: Q86VS1
Gene ID: 5562
Gene Name: PRKAA1
Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Bio References:
Pang,T., J. Biol. Chem. 282 (1), 495-506 (2007)Crawford,R.M., Cell. Signal. 18 (10), 1595-1603 (2006)Crawford,R.M., Mol. Cell. Biol. 26 (15), 5921-5931 (2006)
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