AMPKβ1 (phospho-S181) polyclonal, anti-human, mouse, rat

AMPKβ1 (phospho-S181) polyclonal, anti-human, mouse, rat

€328.00
In stock
SKU
BS4213
Catalog Number: BS4213
Size: 50 ul, 100 ul
Isotype: rabbit IgG
Applications: WB, IHC

Datasheet
Background:
AMPKβ1 is a member of the SNF1 kinase family. It is a heterotrimeric protein comprising of an alpha (catalytic), beta (non-catalytic) and gamma (non-catalytic) subunits, 63, 38 and 38kDa respectively.AMPKβ1 regulates fatty acid and sterol synthesis by phosphorylation of acteyl-coA. It also regulates cholesterol synthesis via phosphorylation and in-activation of hydroxymethylglutaryl-CoA reductase.Two isoforms of AMPKβ1 have been found.

Alternative Name:
5'-AMP-activated protein kinase subunit beta-1, AMPK subunit beta-1, AMPKb, PRKAB1, AMPK, AMPK β1

Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200

Specificity: p-AMPKβ1 (S181) polyclonal antibody detects endogenous levels of AMPKβ1 protein only when phosphorylated at Ser181

Immunogen:
Synthetic phosphopeptide derived from human AMPKβ1 around the phosphorylation site of Serine 181.

MW: ~ 38 kDa

Swis Prot.: Q9Y478

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.
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