ANAPC10 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS71164
Background:
ANAPC10 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the anaphase inhibitor securin (PTTG1; MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1; MIM 123836), the activating subunit of cyclin-dependent kinase-1 (CDK1; MIM 116940) (summary by Wendt et al., 2001
Alternative Name:
DOC1, APC10,
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: ANAPC10 polyclonal antibody detects endogenous levels of ANAPC10 protein.
Immunogen:
Recombinant protein of human ANAPC10.
MW: ~ 21 kDa
Swis Prot.: Q9UM13
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
ANAPC10 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the anaphase inhibitor securin (PTTG1; MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1; MIM 123836), the activating subunit of cyclin-dependent kinase-1 (CDK1; MIM 116940) (summary by Wendt et al., 2001
Alternative Name:
DOC1, APC10,
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: ANAPC10 polyclonal antibody detects endogenous levels of ANAPC10 protein.
Immunogen:
Recombinant protein of human ANAPC10.
MW: ~ 21 kDa
Swis Prot.: Q9UM13
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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