Annexin A11 polyclonal, anti-human

Protein Family: Cytoskeleton Proteins

Pathway and Disease: Signaling Molecules and interaction

Description:
Annexins are a multigene family of Ca++-regulated phospholipid-binding proteins. They serve as membrane-membrane, or membrane-cytoskeleton linkers, and regulate the formation of lipid domains in the plasma membrane. Annexins possess a series of unique 70 amino acid annexin-repeat modules that form a curved disk and allow for the creation of an intercessory complex between plasma membrane and cytofilaments. Annexin A11 binds specifically to calcyclin in a calcium-dependent manner. Annexin A11 is required for midbody formation and completion of the terminal phase of cytokinesis.

Alternate Names: Annexin A11, Annexin-11, Annexin XI, Calcyclin-associated annexin 50, CAP-50, 56 kDa autoantigen, ANXA11, ANX11

Application Notes: E: 1:5,000-1:20,000; WB: 1:100-1:500

Accession No.: P50995

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human annexin A11.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.