Annexin II polyclonal, anti-human

Protein Family: Cytoskeleton Proteins

Pathway and Disease: Signaling Molecules and interaction

Description:
Annexins are a multigene family of Ca++-regulated phospholipid-binding proteins. They serve as membrane-membrane, or membrane-cytoskeleton linkers, and regulate the formation of lipid domains in the plasma membrane. Annexins possess a series of unique 70 amino acid annexin-repeat modules that form a curved disk and allow for the creation of an intercessory complex between plasma membrane and cytofilaments. Annexin II is a heterotetramer containing 2 light chains of S100A10/p11 and 2 heavy chains of ANXA2/p36. Annexin II interacts with ATP1B1 and DYSF. Annexin II also interacts with human cytomegalovirus (HCMV).

Alternate Names: Annexin A2, Annexin-2, Annexin II, Lipocortin II, Calpactin-1 heavy chain, Calpactin I heavy chain, Chromobindin-8, p36, Protein I, Placental anticoagulant protein IV, PAP-IV, ANXA2, ANX2, ANX2L4, CAL1H, LPC2D

Application Notes: E: 1:1,000-1:10,000; WB: 1:100-1:500; IHC: 1:50-1:200

Accession No.: P07355

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Annexin II.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.