Anterior Gradient 2 (AGR2) Antibody (N-term) Blocking peptide

Anterior Gradient 2 (AGR2) Antibody (N-term) Blocking peptide

€293.00
In stock
SKU
AC-BP6279a
Catalog Number: AC-BP6279a
Size: 500 µg
Datasheet

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Background:
Anterior gradient 2 (AGR2) is known as a cancer cell marker specifically up-regulated in response to depletion of serum and oxygen. AGR2 has been identified as a tumor marker in primary and secondary cancer lesions, and as a marker for detection of circulating tumor cells (CTCs). Elevated levels of AGR2 are known to increase the metastatic potential of cancer cells, but conditions leading to increased expression of AGR2 are not well understood.

Other Names: Anterior gradient protein 2 homolog, AG-2, hAG-2, HPC8, Secreted cement gland protein XAG-2 homolog, AGR2, AG2

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6279a was selected from the N-term region of human AGR2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Type: Synthetic peptide

Primary Accession: O95994

Gene ID: 10551

Gene Name: AGR2

Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.

Bio References:
Zweitzig,D.R., Mol. Cell. Biochem. 306 (1-2), 255-260 (2007)Zhang,Y., Prostate Cancer Prostatic Dis. 10 (3), 293-300 (2007)Fletcher,G.C., Br. J. Cancer 88 (4), 579-585 (2003)
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