Antithrombin III (clone 2 E10), anti-human
€747.00
In stock
SKU
250392
Catalog Nr.: 250392
Size: 0.2 mg
Isotype: Mouse IgG1
Applications: E, IHC
Size: 0.2 mg
Isotype: Mouse IgG1
Applications: E, IHC
Protein Family: Enzymes, Peptidases
Pathway and Disease: Signaling Molecules and Interaction, Immune System
Description:
Antithrombin III (AT III) is a single chain glycoprotein of molecular mass 58 kDa with four glycosylation sites and three intra-molecular disulfide bonds. AT III is normally present in human plasma at a concentration of approx. 12.5 mg/dl. It is the major inhibitor of thrombin. Inactivation of thrombin by AT-III occurs by formation of a covalent bond resulting in an inactive 1:1 stoichiometric complex between the two components. This antibody is specific for human AT III in native and denatured forms.
Alternate Names: Antithrombin-III, ATIII, SERPINC1, AT3
Application Notes: Product Cat. No. 250392 reacts strongly in ELISA with both native and denatured AT III directly coated onto the microtiter well, or in sandwich ELISA as detection antibody with a polyclonal capture antibody. E: 1:16,000; IHC: 1:100-1:500
Accession No.: P01008
Antigen: Antithrombin III isolated from human plasma
Format: Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Signaling Molecules and Interaction, Immune System
Description:
Antithrombin III (AT III) is a single chain glycoprotein of molecular mass 58 kDa with four glycosylation sites and three intra-molecular disulfide bonds. AT III is normally present in human plasma at a concentration of approx. 12.5 mg/dl. It is the major inhibitor of thrombin. Inactivation of thrombin by AT-III occurs by formation of a covalent bond resulting in an inactive 1:1 stoichiometric complex between the two components. This antibody is specific for human AT III in native and denatured forms.
Alternate Names: Antithrombin-III, ATIII, SERPINC1, AT3
Application Notes: Product Cat. No. 250392 reacts strongly in ELISA with both native and denatured AT III directly coated onto the microtiter well, or in sandwich ELISA as detection antibody with a polyclonal capture antibody. E: 1:16,000; IHC: 1:100-1:500
Accession No.: P01008
Antigen: Antithrombin III isolated from human plasma
Format: Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
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