AP2 alpha polyclonal, anti-human, rat

Quantity: 100 µg

Background:
TFAP2A, also known as AP-2alpha or BOFS, is a protein that in humans is encoded by the TFAP2A gene. It is mapped to 6p24.3. The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. TFAP2A acts as a sequence-specific DNA-binding transcription factor recognizing and binding to the specific DNA sequence and recruiting transcription machinery. This gene is expressed in neural crest cell lineages with the highest levels of expression corresponding to early neural crest cells, suggesting that TFAP2A plays a role in their differentiation and development.

Description:
Rabbit IgG polyclonal antibody for Transcription factor AP-2-alpha (TFAP2A) detection. Tested with WB in Human, Rat.

Synonyms:
Activating enhancer binding protein 2 alpha antibody, Activating enhancer-binding protein 2-alpha antibody, Activator protein 2 antibody, AP 2 transcription factor antibody, AP 2alpha antibody, AP-2 antibody, AP-2 transcription factor antibody, AP2 antibody, AP2 Transcription Factor antibody, AP2-alpha antibody, AP2A_HUMAN antibody, AP2TF antibody, BOFS antibody, FLJ51761 antibody, TFAP 2 antibody, TFAP 2A antibody, TFAP2 antibody, TFAP2A antibody, Transcription factor AP 2 alpha (activating enhancer binding protein 2 alpha) antibody, Transcription factor AP-2-alpha antibody, Transcription factor AP2 alpha antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human AP2 alpha recombinant protein (Position: M1-G166). Human AP2 alpha shares 98% amino acid (aa) sequence identity with both mouse and rat AP2 alpha.E.coli-derived human AP2 alpha recombinant protein (Position: M1-G166). Human AP2 alpha shares 98% amino acid (aa) sequence identity with both mouse and rat AP2 alpha.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.