AP2A1 Polyclonal Antibody

Background:
This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms. A third transcript variant has been described, but its full length nature has not been determined.

Research Area: Cancer, Signal transduction

Synonyms:
AP2A1, ADTAA, AP2-ALPHA, CLAPA1

Immunogen: Recombinant fusion protein of human AP2A1 (NP_055018.2).

Swissprot: O95782
Gene ID: 160

Calculated MW: 105 kDa/107 kDa
Observed MW: 108 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.