AP2M1 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Three transcript variants encoding different isoforms have been found for this gene.

Synonyms: AP50, CLAPM1, mu2

Cellular Location: Cell membrane Cytoplasmic side Membrane Peripheral membrane protein coated pit

Immunogen:
Recombinant protein of human AP2M1

Gene Symbol: AP2M1

Gene ID: 1173

Swiss prot: Q96CW1

Calculated MW: 50kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.