AP3 polyclonal, anti-human
€347.00
In stock
SKU
252072
Catalog Nr.: 252072
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB
Protein Family: Transporters
Pathway and Disease: Membrane Transport
Description:
Adaptor protein complex 3 (AP-3) is a heterotetramer composed of two large adaptins (delta-type subunit AP3D1 and beta-type subunit AP3B1 or AP3B2), a medium adaptin (mu-type subunit AP3M1 or AP3M2) and a small adaptin (sigma-type subunit APS1 or AP3S2). The complex is associated with the Golgi region as well as more peripheral structures. AP-3 facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.
Alternate Names: AP3D1, AP-3 complex subunit delta-1, Adapter-related protein complex 3 subunit delta-1, Delta-adaptin, AP3, AP3B1, AP3B2, AP3M1, AP3M2, APS1, AP3S2
Application Notes: E: 1:10,000-1:50,000; WB: 1:100-1:1,000
Accession No.: O14617
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human AP3D1.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Membrane Transport
Description:
Adaptor protein complex 3 (AP-3) is a heterotetramer composed of two large adaptins (delta-type subunit AP3D1 and beta-type subunit AP3B1 or AP3B2), a medium adaptin (mu-type subunit AP3M1 or AP3M2) and a small adaptin (sigma-type subunit APS1 or AP3S2). The complex is associated with the Golgi region as well as more peripheral structures. AP-3 facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.
Alternate Names: AP3D1, AP-3 complex subunit delta-1, Adapter-related protein complex 3 subunit delta-1, Delta-adaptin, AP3, AP3B1, AP3B2, AP3M1, AP3M2, APS1, AP3S2
Application Notes: E: 1:10,000-1:50,000; WB: 1:100-1:1,000
Accession No.: O14617
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human AP3D1.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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