AP3B2 polyclonal, anti-human, mouse, rat
€484.00
In stock
SKU
254489
Protein Family: Enzymes
Pathway and Disease: Signaling Molecules and Interaction
Description:
The AP3 complex is a heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Unlike the homologous AP3B1, AP3B2-containing AP3 complexes are preferentially targeted to neuronal processes, and mice deficient in AP3B2 displayed compromised synaptic zinc stores.
Alternate Names: Adaptor-related protein complex 3 beta-2 subunit, AP-3 complex subunit beta-2, NAPTB, Beta3B
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human AP3B2.
Format: Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Signaling Molecules and Interaction
Description:
The AP3 complex is a heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Unlike the homologous AP3B1, AP3B2-containing AP3 complexes are preferentially targeted to neuronal processes, and mice deficient in AP3B2 displayed compromised synaptic zinc stores.
Alternate Names: Adaptor-related protein complex 3 beta-2 subunit, AP-3 complex subunit beta-2, NAPTB, Beta3B
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human AP3B2.
Format: Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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