APC Anti-Human CD133 Antibody [clone W6B3C1]

Background:
CD133, also known as Prominin-1 and AC133 antigen, is a 120 kD pentaspan glycoprotein with 5 transmembrane domains. CD138 was initially described as a surface antigen specific for human hematopoietic stem cells and as a marker for murine neuroepithelial cs and some embryonic epithelia. Later on, CD133 was found on other stem cells, including endothelial progenitor cells, glioblastomas, neuronal, and glial stem cells. In addition to stem cells for normal tissue, CD133 was found on cancer cells, such as some leukemia cells and brain tumor cells. Although the biological function of CD133 is not completely understood, CD133 has been extensively used as a stem cell marker for normal and cancerous tissues.

Synonyms:
Prominin-1, PROM1, AC133
Swissprot: O43490

Buffer: PBS with 0.05% Proclin300, 1% BSA

Storage:
Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.