APC5 Polyclonal Antibody

Background:
This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Area: Cell Biology

Synonyms:
2510006G12Rik, AA408751, AA536819, AA986414, ANAPC 5, ANAPC5, Anaphase promoting complex subunit 5, Anaphase-promoting complex subunit 5, Apc 5, APC5, APC5, Cyclosome subunit 5, PDL 108, PDL108, Periodontal ligament fibroblast protein, RMC1

Immunogen: Recombinant protein of human ANAPC5

Swissprot: Q9UJX4
Gene Accession: BC006301

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-21417/sc-20986