APC5 Polyclonal Antibody

Background:
anaphase promoting complex subunit 5(ANAPC5) Homo sapiens This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq, Nov 2008],

Alternative Names:
ANAPC5, APC5, Anaphase-promoting complex subunit 5, APC5, Cyclosome subunit 5

Immunogen: The antiserum was produced against synthesized peptide derived from human ANAPC5. AA range:151-200

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 85

GeneID: ANAPC5

Storage: -20°C/1 year

NOTE: For Research Use Only