APCS polyclonal (C-term), anti-human
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In stock
SKU
AC-AP10677b
Catalog Number: AC-AP10677b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB28441
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB28441
Applications: IHC-P, WB
Datasheet
Request Information
Background:
The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.
Other Names:
Serum amyloid P-component, SAP, 95S alpha-1-glycoprotein, Serum amyloid P-component(1-203), APCS, PTX2
Target/Specificity:
This APCS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-178 amino acids from the C-terminal region of human APCS.
Antigen Region:
151-178
Antigen Type: Synthetic Peptide
Gene Name: APCS
Gene ID: 325
Primary Accession: P02743
NCBI Accession: NP_001630.1
Other Accession: Q13449; NP_001630.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.
Other Names:
Serum amyloid P-component, SAP, 95S alpha-1-glycoprotein, Serum amyloid P-component(1-203), APCS, PTX2
Target/Specificity:
This APCS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-178 amino acids from the C-terminal region of human APCS.
Antigen Region:
151-178
Antigen Type: Synthetic Peptide
Gene Name: APCS
Gene ID: 325
Primary Accession: P02743
NCBI Accession: NP_001630.1
Other Accession: Q13449; NP_001630.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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