ApoA5 (clone 4H8H8E2 (c)), anti-human
€491.00
In stock
SKU
252597
Catalog Nr.: 252597
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: E, WB
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: E, WB
Protein Family: Chaperones and Folding Catalysts
Pathway and Disease: Endocrine System
Description:
ApoA5 (Apolipoprotein A5) is a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50–70% lower concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor-agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. ApoA5 is present in human serum detected by polyclonal antibodies against both the NH2 and COOH termini, although at much lower concentration than other apolipoproteins.
Alternate Names: Apolipoprotein A-V, Apo-AV, ApoA-V, Apolipoprotein A5, Regeneration-associated protein 3, RAP3, APOA5
Application Notes: ELISA: 1:5000; WB: 1:500-1:2000
Accession No.: Q6Q788
Antigen: Purified recombinant fragment of human APOA5 expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Endocrine System
Description:
ApoA5 (Apolipoprotein A5) is a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50–70% lower concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor-agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. ApoA5 is present in human serum detected by polyclonal antibodies against both the NH2 and COOH termini, although at much lower concentration than other apolipoproteins.
Alternate Names: Apolipoprotein A-V, Apo-AV, ApoA-V, Apolipoprotein A5, Regeneration-associated protein 3, RAP3, APOA5
Application Notes: ELISA: 1:5000; WB: 1:500-1:2000
Accession No.: Q6Q788
Antigen: Purified recombinant fragment of human APOA5 expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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