APOC3 Antibody (C-term) Blocking Peptide

APOC3 Antibody (C-term) Blocking Peptide

€293.00
In stock
SKU
AC-BP7797b
Catalog Number: AC-BP7797b
Size: 500 µg
Datasheet

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Background:
Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia.

Other Names: Apolipoprotein C-III, Apo-CIII, ApoC-III, Apolipoprotein C3, APOC3

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7797b was selected from the C-term region of human APOC3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Type: Synthetic peptide

Primary Accession: P02656

Gene ID: 345

Gene Name: APOC3

Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.

Bio References:
Liu,Y., Pharmacogenet. Genomics 19 (2), 161-169 (2009)Pollin,T.I., Science 322 (5908), 1702-1705 (2008)
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