APPBP1 Antibody (Center) Blocking Peptide
€293.00
In stock
SKU
AC-BP7273c
Background:
APPBP1 binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, this protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. APPBP1 is required for cell cycle progression through the S/M checkpoint.
Other Names: NEDD8-activating enzyme E1 regulatory subunit, Amyloid beta precursor protein-binding protein 1, 59 kDa, APP-BP1, Amyloid protein-binding protein 1, Proto-oncogene protein 1, NAE1, APPBP1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7273c was selected from the Center region of human APPBP1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: Q13564
Other Accession: NP_003896
Gene ID: 8883
Gene Name: NAE1
Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Bio References:
Chen,Y., J. Cell Biol. 163 (1), 27-33 (2003)Chen,Y., J. Neurochem. 85 (3), 801-809 (2003)Walden,H., Nature 422 (6929), 330-334 (2003)Chow,N., J. Biol. Chem. 271 (19), 11339-11346 (1996)
APPBP1 binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, this protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. APPBP1 is required for cell cycle progression through the S/M checkpoint.
Other Names: NEDD8-activating enzyme E1 regulatory subunit, Amyloid beta precursor protein-binding protein 1, 59 kDa, APP-BP1, Amyloid protein-binding protein 1, Proto-oncogene protein 1, NAE1, APPBP1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7273c was selected from the Center region of human APPBP1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: Q13564
Other Accession: NP_003896
Gene ID: 8883
Gene Name: NAE1
Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Bio References:
Chen,Y., J. Cell Biol. 163 (1), 27-33 (2003)Chen,Y., J. Neurochem. 85 (3), 801-809 (2003)Walden,H., Nature 422 (6929), 330-334 (2003)Chow,N., J. Biol. Chem. 271 (19), 11339-11346 (1996)
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