APRT Antibody (N-term) Blocking Peptide
€293.00
In stock
SKU
AC-BP2893a
Background:
A conserved feature of APRT is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis.
Other Names: Adenine phosphoribosyltransferase, APRT, APRT
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2893a was selected from the N-term region of human APRT. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: P07741
Gene ID: 353
Gene Name: APRT
Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Bio References:
Silva,C.H., etc,J. Biomol. Struct. Dyn. 25 (6), 589-597 (2008)Di Pietro,V., etc,Clin. Biochem. 40 (1-2), 73-80 (2007)
A conserved feature of APRT is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis.
Other Names: Adenine phosphoribosyltransferase, APRT, APRT
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2893a was selected from the N-term region of human APRT. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: P07741
Gene ID: 353
Gene Name: APRT
Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Bio References:
Silva,C.H., etc,J. Biomol. Struct. Dyn. 25 (6), 589-597 (2008)Di Pietro,V., etc,Clin. Biochem. 40 (1-2), 73-80 (2007)
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