AQP1 polyclonal, anti-human, mouse, rat

Protein Family: Receptors and Channels

Pathway and Disease: Membrane Transport

Description:
Aquaporin-1 (AQP1) forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. AQP1 is responsible for the Colton blood group system. Approximately 92% of Caucasians are Co(A+B-) (Ala-46), approximately 8% are Co(A+B+), and only 0.2% are Co(A-B+) (Val-46). Co(A-B-), which is very rare, is due to a complete absence of AQP1. AQP1 is pharmacologically inhibited by submillimolar concentrations of mercury.

Alternate Names: Aquaporin-1, AQP-1, Aquaporin-CHIP, Water channel protein for red blood cells and kidney proximal tubule, Urine water channel, AQP1, CHIP28

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; ICC: 1:100-1:500

Accession No.: P29972

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human AQP1.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 5% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.