AQP4 polyclonal, anti-human, mouse, rat, bovine

Protein Family: Receptors and Channels

Pathway and Disease: Membrane Transport, Nervous and Sensory Systems

Description:
Aquaporin-4 (AQP4) is an osmoreceptor that forms a water-specific channel to regulate body water balance and to mediate water flow within the central nervous system. AQP4 is predominantly expressed in the ependymal cells lining the aqueductal system and over the space of the brain in contact with the subarachnoid space. As cerebrospinal fluid fills these structures, AQP4 facilitates water balance between brain parenchyma and fluid compartment.

Alternate Names: Aquaporin-4, AQP-4, WCH4, Mercurial-insensitive water channel, MIWC, AQP4

Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500

Accession No.: P55087

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of mouse AQP4.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.