AQP4 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS6970
Background:
In skeletal muscle, AQP4 (aquaporin 4 also known as mercurial insensitive water channel), localizes to the sarcolemma of fast-twitch muscle fibers. Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane. This function is conserved in animals, plants and bacteria. Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol.
Alternative Name:
Aquaporin 4, Aquaporin4, Aquaporin-4, AQP-4, Mercurial-insensitive water channel, MIWC, WCH4, AQP4
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: AQP4 polyclonal antibody detects endogenous levels of AQP4 protein.
Immunogen:
Recombinant full length Human AQP4.
MW: ~ 35 kDa
Swis Prot.: P55087
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
In skeletal muscle, AQP4 (aquaporin 4 also known as mercurial insensitive water channel), localizes to the sarcolemma of fast-twitch muscle fibers. Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane. This function is conserved in animals, plants and bacteria. Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol.
Alternative Name:
Aquaporin 4, Aquaporin4, Aquaporin-4, AQP-4, Mercurial-insensitive water channel, MIWC, WCH4, AQP4
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: AQP4 polyclonal antibody detects endogenous levels of AQP4 protein.
Immunogen:
Recombinant full length Human AQP4.
MW: ~ 35 kDa
Swis Prot.: P55087
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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