AR-β2 (phospho Ser355/S356) Polyclonal Antibody

AR-β2 (phospho Ser355/S356) Polyclonal Antibody

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In stock
SKU
ELK-ES4918
Catalog Number: ELK-ES4918
Reactivity: Human, Mouse, Rat, Monkey
Applications: WB, IHC-p, ELISA
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Background:
adrenoceptor beta 2(ADRB2) Homo sapiens This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Jul 2008],

Alternative Names:
ADRB2, ADRB2R, B2AR, Beta-2 adrenergic receptor, Beta-2 adrenoreceptor, Beta-2 adrenoceptor

Immunogen: The antiserum was produced against synthesized peptide derived from human Adrenergic Receptor B2 around the phosphorylation site of Ser355 and Ser356. AA range:331-380

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 47

GeneID: ADRB2

Storage: -20°C/1 year

NOTE: For Research Use Only
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