ARHG7 Antibody (N-term) Blocking Peptide
€293.00
In stock
SKU
AC-BP7992a
Background:
Rho GTPases play a fundamental role in numerous cellular processes triggered by extracellular stimuli that work through G protein coupled receptors. ARHG7 belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. This protein can induce membrane ruffling.
Other Names: Rho guanine nucleotide exchange factor 7, Beta-Pix, COOL-1, PAK-interacting exchange factor beta, p85, ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7992a was selected from the N-term region of human ARHG7. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: Q14155
Gene ID: 8874
Gene Name: ARHGEF7
Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Bio References:
Flaiz,C., Brain Pathol. 19 (1), 27-38 (2009)Eitel,J., J. Immunol. 181 (4), 2664-2671 (2008)
Rho GTPases play a fundamental role in numerous cellular processes triggered by extracellular stimuli that work through G protein coupled receptors. ARHG7 belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. This protein can induce membrane ruffling.
Other Names: Rho guanine nucleotide exchange factor 7, Beta-Pix, COOL-1, PAK-interacting exchange factor beta, p85, ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7992a was selected from the N-term region of human ARHG7. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: Q14155
Gene ID: 8874
Gene Name: ARHGEF7
Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Bio References:
Flaiz,C., Brain Pathol. 19 (1), 27-38 (2009)Eitel,J., J. Immunol. 181 (4), 2664-2671 (2008)
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