ARL2 Antibody (N-term) Blocking Peptide
€293.00
In stock
SKU
AC-BP2305a
Background:
ADP-ribosylation factors (ARFs) regulate intracellular vesicular membrane trafficking and stimulate a phospholipase D isoform. ARL (ADP-ribosylation like factor) proteins are very similar in sequence to ARFs. ARFs and ARF-like (ARL) proteins, which share sequence similarity with ARFs, form a subfamily of the Ras-related GTPase superfamily. ARL2 encodes a ubiquitiously expressed 184-amino acid predicted protein that is 76% identical to ARF1 and 40 to 45% identical to the Drosophila ARL proteins. Recombinant ARL2 binds to GTP rapidly but guanine nucleotide exchange does not require phospholipids, which is a characteristic of the ARF proteins.
Other Names: ADP-ribosylation factor-like protein 2, ARL2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2305a was selected from the N-term region of human ARL2 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: P36404
Other Accession: NP_001658
Gene ID: 402
Gene Name: ARL2
Format: The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
Bio References:
Antoshechkin, I., et al., Dev. Cell 2(5):579-591 (2002).Bhamidipati, A., et al., J. Cell Biol. 149(5):1087-1096 (2000).Clark, J., et al., Proc. Natl. Acad. Sci. U.S.A. 90(19):8952-8956 (1993).
ADP-ribosylation factors (ARFs) regulate intracellular vesicular membrane trafficking and stimulate a phospholipase D isoform. ARL (ADP-ribosylation like factor) proteins are very similar in sequence to ARFs. ARFs and ARF-like (ARL) proteins, which share sequence similarity with ARFs, form a subfamily of the Ras-related GTPase superfamily. ARL2 encodes a ubiquitiously expressed 184-amino acid predicted protein that is 76% identical to ARF1 and 40 to 45% identical to the Drosophila ARL proteins. Recombinant ARL2 binds to GTP rapidly but guanine nucleotide exchange does not require phospholipids, which is a characteristic of the ARF proteins.
Other Names: ADP-ribosylation factor-like protein 2, ARL2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2305a was selected from the N-term region of human ARL2 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: P36404
Other Accession: NP_001658
Gene ID: 402
Gene Name: ARL2
Format: The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
Bio References:
Antoshechkin, I., et al., Dev. Cell 2(5):579-591 (2002).Bhamidipati, A., et al., J. Cell Biol. 149(5):1087-1096 (2000).Clark, J., et al., Proc. Natl. Acad. Sci. U.S.A. 90(19):8952-8956 (1993).
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