ARL6 Antibody (C-term) Blocking Peptide
€293.00
In stock
SKU
AC-BP2309b
Background:
ARL6 belongs to the ARF family of GTP-binding proteins. ARF proteins are important regulators of cellular traffic and are the founding members of an expanding family of homologous proteins and genomic sequences. They depart from other small GTP-binding proteins by a unique structural device that implements front-back communication from the N-terminus to the nucleotide-binding site. Studies of the mouse ortholog of this protein suggest an involvement in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been described.
Other Names: ADP-ribosylation factor-like protein 6, Bardet-Biedl syndrome 3 protein, ARL6, BBS3
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2309b was selected from the C-term region of human ARL6 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: Q9H0F7
Gene ID: 84100
Gene Name: ARL6
Format: The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
Bio References:
Pasqualato, S., et al., EMBO Rep. 3(11):1035-1041 (2002).Ingley, E., et al., FEBS Lett. 459(1):69-74 (1999).Jacobs, S., et al., FEBS Lett. 456(3):384-388 (1999).
ARL6 belongs to the ARF family of GTP-binding proteins. ARF proteins are important regulators of cellular traffic and are the founding members of an expanding family of homologous proteins and genomic sequences. They depart from other small GTP-binding proteins by a unique structural device that implements front-back communication from the N-terminus to the nucleotide-binding site. Studies of the mouse ortholog of this protein suggest an involvement in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been described.
Other Names: ADP-ribosylation factor-like protein 6, Bardet-Biedl syndrome 3 protein, ARL6, BBS3
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2309b was selected from the C-term region of human ARL6 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: Q9H0F7
Gene ID: 84100
Gene Name: ARL6
Format: The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
Bio References:
Pasqualato, S., et al., EMBO Rep. 3(11):1035-1041 (2002).Ingley, E., et al., FEBS Lett. 459(1):69-74 (1999).Jacobs, S., et al., FEBS Lett. 456(3):384-388 (1999).
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