Aromatase (CYP19A1) Antibody (Center) Blocking peptide

Aromatase (CYP19A1) Antibody (Center) Blocking peptide

€293.00
In stock
SKU
AC-BP7293c
Catalog Number: AC-BP7293c
Size: 500 µg
Datasheet

Request Information
Background:
CYP19A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation.

Other Names: Aromatase, CYPXIX, Cytochrome P-450AROM, Cytochrome P450 19A1, Estrogen synthase, CYP19A1, ARO1, CYAR, CYP19

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7293c was selected from the Center region of human CYP19A1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Type: Synthetic peptide

Primary Accession: P11511

Gene ID: 1588

Gene Name: CYP19A1 {ECO:0000303|PubMed:24705274, ECO:0000312|HGNC:HGNC:2594}

Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.

Bio References:
Ikeda,S.,Am. J. Gastroenterol. 103 (6), 1476-1487 (2008)Dos Santos,(er) DNA Cell Biol. (2008) In pressNelson,Pharmacogenetics 14 (1), 1-18 (2004)
More Information
Is Featured? No
Write Your Own Review
You're reviewing:Aromatase (CYP19A1) Antibody (Center) Blocking peptide